Broad Research Focus

1. Cardiac Imaging
2. Neuroradiology
3. Breast Imaging
4. Image Quality Assessment
5. Image Guided Radiotherapy
6. Application of Physics and Mathematics to Problems in Medical Physics

Projects

• Time Resolved Imaging: Neuro and Cardiac Cone-beam CT (CBCT) and Multidetector CT (MDCT)
  • CBCT-Angiography
  • CBCT-Perfusion
  • Stroke: One-Stop-Shop Imaging
  • Ultra-High Temporal Resolution Cardiac CT Coronary Angiography
  • Interventional imaging
  • Bench-top X-ray CT system experiments
• Multi-contrast x-ray imaging
  • Phase contrast and dark field breast imaging
  • Prototype systems
  • Novel system design
    • Gratings
    • Photon counting detectors (PCD)
• Image Reconstruction Algorithms: Analytical Image Reconstruction Methods, Model Based Image Reconstruction Methods, and Deep Learning Based Intelligent CT Image Reconstruction Methods
• Photon-counting x-ray and CT imaging
  • Physics Modeling
  • Advanced Applications
• Image quality assessment and evaluation
  • Noise and spatial resolution dependence
  • CT number accuracy
  • Model observers (e.g. high spat. res tasks)
  • Dual energy CT
  • Evaluation of current clinical systems
• Artificial Intelligence (AI) and Applications in Medical Imaging
  • Virtual Radiologist Development
  • Virtual Medical Physicist Development

Enabling technologies for the projects/applications above

• (Software) Image reconstruction and artifact reduction methods
  • Iterative methods: PICCS, DOS-SPART, SMART-RECON
  • Low signal correction (LSC)
  • Digital breast tomosynthesis (DBT)
  • CT reconstruction using artificial intelligence (AI)
  • Deep learning angiography (DLA)
• (Hardware) Imaging facilities, systems, detectors, and computing resources
  • MDCT scanners from GE—Discovery CT750 HD and Revolution CT
  • Siemens Angio Suite
  • Hologic Mammography system
  • Benchtop conventional X-Ray/CT system
  • Benchtop phase contrast X-Ray/CT system
  • Varian G-1592 X-Ray Tube
  • CsI + a-Si based energy integrating detector (model PaxScan 4030CB, from Varian Medical Systems)
  • CdTe-based photon counting detector (model XC-XFLITE X1, from XCounter AB)
  • Multiple anthropomorphic and calibration phantoms and other imaging materials
  • Multi-GPU enabled workstations